27.04.2010 | 18.45hs. (23.45 GMT)   | San Luis FC vs. Estudiantes de La Plata
27.04.2010 | 21.00hs. (02.00+ GMT) | Chivas Guadalajara vs. Vélez Sarsfield
28.04.2010 | 17.30hs. (22.30 GMT)   | Universitario vs. Sao Paulo FC
28.04.2010 | 21.50hs. (00.50+ GMT) | Flamengo vs. Corinthians
28.04.2010 | 21.50hs. (00.50+ GMT) | CA Banfield vs. Internacional
29.04.2010 | 19.00hs. (22.00 GMT)   | Cruzeiro vs. Nacional
29.04.2010 | 19.15hs. (00.15+ GMT) | Alianza Lima vs. Universidad de Chile
29.04.2010 | 21.30hs. (02.30+ GMT) | Once Caldas vs. Libertad